Polynucleotides for the face in London

Usually, yes. Most people who search for a polynucleotide facial mean injections across the face by a doctor or nurse, and that is what the practices at UNTIL Marylebone and UNTIL Soho give. A salon facial with a serum labelled PDRN or salmon DNA is skincare applied to the surface, which costs less and has not been shown to do the same. Salmon sperm injections sets out the difference.

A full-face course treats the whole surface of the skin, with more attention where it is thinnest or most marked. This is what polynucleotides can change in each area.

Forehead lines

Fine lines etched into thin forehead skin soften as the skin thickens. Lines that deepen only when you frown or raise your brows come from the muscle beneath, which polynucleotides do not affect, so a practitioner may suggest a different treatment for those.

Crow's feet and the under-eye

The skin around the eyes is the thinnest on the face. In a 2022 study of 30 people with crow's feet, 3D camera measurements showed finer wrinkles, smoother texture and smaller-looking pores at 18 weeks, though the study had no comparison group. Polynucleotides under eyes in London covers this area in detail.

Smile lines and nasolabial folds

The folds from nose to mouth come mostly from volume and support lost in the cheek above, so filler is the usual treatment for a deep fold. In a small 2023 study of 20 women with deep folds, polynucleotides on their own improved the skin's texture within six weeks, and given before a filler they appeared to make the filler last longer. They help the skin over a fold more than the fold itself.

Acne scars

In a small 2021 study, 20 women with moderate to severe acne scars were randomly given polynucleotides or a saline placebo, and only the polynucleotide group improved significantly at one and three months. They help rolling scars and scarred, uneven skin most; deep ice-pick scars usually need resurfacing or microneedling as well. The practitioner will want any active acne settled first.

Skin texture and large pores

Dull, rough or uneven skin is what a full-face course changes most reliably. Pores look smaller as the skin around them firms, though their size is set largely by genetics and oil, so expect them to look finer rather than to disappear.

In the first days the small bumps from the injections settle. Little else shows for two to three weeks. From around week four most people notice brighter, more even skin, and by weeks eight to twelve it looks and feels firmer, with softer fine lines and smoother texture. Scarring and deeper lines change more slowly and less completely. Compare before-and-after photographs only when they were taken in the same light and at the same angle, and ask the practitioner for their own. The published studies describe what groups of patients saw.

The practices London Polynucleotides connects you with publish polynucleotides for the face at £220 to £350 a session, and a course of three at £600 to £750, checked on 1 October 2026. A doctor-led practice publishes a maintenance session at £275. Ask whether a quote covers the full face or one area, and how many sessions it assumes. Polynucleotide prices in London lists every published figure.

Practices at UNTIL Marylebone, 1 Orchard Street, near Bond Street, and at UNTIL Soho, 111 Charing Cross Road, near Tottenham Court Road, publish polynucleotides for the face. Choose either club on the enquiry form, and UNTIL Health Concierge will arrange the assessment.