Salmon sperm injections in London

The two names get used for different things, and the difference matters to the result and the price.

Salmon sperm injections

Injections of polynucleotide gel into the skin by a practitioner, usually a doctor or nurse, as a course of three. This is what the published studies measure, and what the practices at UNTIL Marylebone and UNTIL Soho give. Many people who say salmon sperm facial mean this.

Salmon DNA serums and skincare

Serums and creams labelled PDRN or salmon DNA are skincare, applied to the surface at home or during a salon facial. They are much cheaper than injections. How much of the DNA reaches the deeper skin from a cream has not been shown in the research on injections, so do not expect the same change.

Facials that add microneedling

Some clinics apply a polynucleotide product during microneedling, which opens tiny channels in the skin. One Soho practice publishes a combined regenerative session of microneedling, exosomes and polynucleotides at £450. Ask exactly what is being applied and how before you compare prices.

Expect gradual, quiet change rather than a dramatic reveal. The first fortnight after the first session shows little beyond small bumps that settle in a few days. After the second session, around week four, skin usually looks brighter and less dull. By weeks eight to twelve, fine crepey lines are softer and under-eye shadows from thin skin are less obvious. Photographs online that show a big difference in a week are usually showing swelling, make-up or better light. Ask the practitioner for their own before-and-after pictures, taken at week eight or later in the same light.

The effects are the same as any polynucleotide treatment: small raised bumps for one to three days, some redness and swelling, and bruising, most often under the eyes. Because the material comes from fish, a fish allergy rules the treatment out, and a practitioner should ask about it before anything else. Infection and lasting lumps are uncommon and depend mostly on technique. Polynucleotides side effects and aftercare covers the days after a session in detail.

At the practices London Polynucleotides connects you with, salmon sperm injections cost £220 to £350 a session, and a course of three starts at £600. These are the practitioners' own published prices for polynucleotides, checked on 29 September 2026. A salon facial with a salmon DNA serum costs less because it is skincare, not an injection. Polynucleotide prices in London breaks the figures down by area.

Practices publish the treatment at UNTIL Marylebone, 1 Orchard Street, 8 minutes on foot from Bond Street, and at UNTIL Soho, 111 Charing Cross Road, about 150 metres from Tottenham Court Road. Choose either club on the enquiry form.